B variant GM2 gangliosidosis
noun [ U ] medical specialized uk/ˌbiː veə.ri.ənt dʒiː.emˌtuː ˌɡæŋ.ɡli.əʊ.sɪˈdəʊ.sɪs/ us/ˌbi ver.i.ənt dʒiː.emˌtuː ˌɡæŋ.ɡli.oʊ.sɪˈdoʊ.sɪs/ (also Tay-Sachs disease); (abbreviation TD)
GM2神经节苷脂病变异型B，GM2神经节苷脂沉积症变异型B
a genetic disease in which the body is unable to get rid of a fatty substance called ganglioside so that it builds up in the brain. This causes the nerves to stop working properly and eventually leads to death, usually before the age of three