world-weary
adjective uk/ˈwɜːldˌwɪə.ri/ us/ˈwɝːldˌwɪr.i/
厌世的;厌弃人生的
Someone who is world-weary is not enthusiastic about anything, often because they have had too much experience of a particular way of life.
15 years in the teaching profession had left him world-weary and cynical. 15年的执教生涯使他悲观厌世、愤世疾俗。